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咗他莫司 Zotarolimus

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產(chǎn)品信息

產(chǎn)品名稱：咗他莫司 Zotarolimus	純度：99% min
CAS NO：221877-54-9	溶解度：DMSO: ≥ 33 mg/mL
分子式：C₅₂H₇₉N₅O₁₂	包裝：可按客戶要求包裝
分子量：966.21	貯存：-20℃

質量控制

備注說明

Zotarolimus, also known as ABT-578 and A-179578, is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Coronary stents reduce early complications and improve late clinical outcomes in patients needing interventional cardiology. Medtronic are using zotarolimus as the anti-proliferative agent in the polymer coating of their Endeavor and Resolute products.

咗他莫司Zotarolimus 是雷帕霉素類似物。

物化屬性:

密度：1.25

沸點：1016.2°Cat760mmHg

閃光點：568.4°C

PSA：218.80000

LOGP：5.98540

參考文獻

[1]. Wagner R et al. Rapamycin analogs with reduced systemic exposure. et al. Bioorg Med Chem Lett. 2005 Dec 1, 15(23), 5340-3.